Recombinant Human Anti-IL23 x Human Anti-IL6 Bispecific Antibody (F(ab')2-scFv2) (BABFV-H343)

Recombinant Anti-IL23 x Anti-IL6 Bispecific Antibody (F(ab')2-scFv2) is designed to be expressed as two chains combined via a hinge region. The scFv of the anti-IL23 specificity is fused to the C terminus of the anti-IL6 Fab fragment, or vice versa. This format comprises four binding sites (two same scFv regions and two same Fab fragments), two for each antigen. This BsAb can block two proinﬂammatory cytokines simultaneously. It is designed for the research of Inflammatory diseases therapy.

Datasheet INQUIRY

Specifications

Targets

IL23 & IL6

Type

Fab-Fc Fusion Proteins

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Inflammatory diseases

Targets

Target 1

IL23

Gene ID

51561

UniProt ID

Q9NPF7

Alternative Names

P19; SGRF; IL-23; IL-23A; IL23P19; Interleukin-23; IL23; interleukin 23 subunit alpha

Target 2

IL6

Gene ID

3569

UniProt ID

P05231

Alternative Names

CDF; HGF; HSF; BSF2; IL-6; BSF-2; IFNB2; IFN-beta-2; interleukin 6; IL6

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Human Anti-IL23 x Human Anti-IL6 Bispecific Antibody (F(ab')2-scFv2) (CAT#: BABFV-H343)

Specifications

Targets

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