Name: Recombinant Human Anti-IL23 x Human Anti-IL6 Bispecific Antibody (Fab-scFv-Fc)
SKU: FABVC-H343
Rating: 5 (1 reviews)

Recombinant Anti-IL23 x Anti-IL6 Bispecific Antibody (Fab-scFv-Fc) requires expression of three polypeptide chains, encoding two heavy chains (Fc-containing chains) and one light chain, respectively. The Fab of anti-IL23 antibody variable domain is fused to the Fc-knob domain with a hinge region and the same as the scFv of anti-IL6 to the Fc-hole domain, or vice versa. The Fab-Fc and scFv-Fc fragments can be paired via the interaction of the Fc regions. This BsAb can block two proinﬂammatory cytokines simultaneously. It is designed for the research of Inflammatory diseases therapy.

Datasheet INQUIRY

Specifications

Targets

IL23 & IL6

Type

Fab-Fc Fusion Proteins

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Inflammatory diseases

Targets

Target 1

IL23

Gene ID

51561

UniProt ID

Q9NPF7

Alternative Names

P19; SGRF; IL-23; IL-23A; IL23P19; Interleukin-23; IL23; interleukin 23 subunit alpha

Target 2

IL6

Gene ID

3569

UniProt ID

P05231

Alternative Names

CDF; HGF; HSF; BSF2; IL-6; BSF-2; IFNB2; IFN-beta-2; interleukin 6; IL6

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Human Anti-IL23 x Human Anti-IL6 Bispecific Antibody (Fab-scFv-Fc) (CAT#: FABVC-H343)

Specifications

Targets

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