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Recombinant Anti-IL23 x Anti-IL6 Bispecific Antibody (scFv-CH3)  (CAT#: BSFC-178)

Recombinant Anti-IL23 x Anti-IL6 Bispecific Antibody (scFv-CH3) contains two chains. The anti-IL23 scFv is fused to the Knob-CH3 domain via a hinge region and the same as the anti-IL6 scFv to the Hole-CH3 domain, or vice versa. The KIH CH3 domains can facilitate to form a heterodimer and this bivalent binding leads to improvement in avidity. This BsAb can block two proinflammatory cytokines simultaneously. It is designed for the research of Inflammatory diseases therapy.
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Specifications

Targets
IL23 & IL6
Type
scFv-based Bispecific Fragments
Species Reactivity
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Inflammatory diseases

Targets

Target 1
IL23
Gene ID
UniProt ID
Alternative Names
P19; SGRF; IL-23; IL-23A; IL23P19; Interleukin-23; IL23; interleukin 23 subunit alpha
Target 2
IL6
Gene ID
UniProt ID
Alternative Names
CDF; HGF; HSF; BSF2; IL-6; BSF-2; IFNB2; IFN-beta-2; interleukin 6; IL6
Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.
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