Name: Recombinant Human Anti-IL23 x Human Anti-IL6 Bispecific Antibody (scFv-Fc-scFv)
SKU: BSTF-H343
Rating: 5 (1 reviews)

Recombinant Anti-IL23 x Anti-IL6 Bispecific Antibody (scFv-Fc-scFv) is designed to be expressed as one chain, then assembled to a homodimer of bivalent scFv fragments and the Fc region of IgG. The anti-IL23 scFv is fused to the N-terminus of Fc via a hinge region while another anti-IL6 scFv is linked to the C-terminus of Fc. This scFv-Fc-scFv format has 2+2 antigen-binding valency by employing different scFv fragments. This BsAb can block two proinﬂammatory cytokines simultaneously. It is designed for the research of Inflammatory diseases therapy.

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Specifications

Targets

IL23 & IL6

Type

scFv-based Bispecific Fragments

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Inflammatory diseases

Targets

Target 1

IL23

Gene ID

51561

UniProt ID

Q9NPF7

Alternative Names

P19; SGRF; IL-23; IL-23A; IL23P19; Interleukin-23; IL23; interleukin 23 subunit alpha

Target 2

IL6

Gene ID

3569

UniProt ID

P05231

Alternative Names

CDF; HGF; HSF; BSF2; IL-6; BSF-2; IFNB2; IFN-beta-2; interleukin 6; IL6

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Human Anti-IL23 x Human Anti-IL6 Bispecific Antibody (scFv-Fc-scFv) (CAT#: BSTF-H343)

Specifications

Targets

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