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Recombinant Anti-INSR x Anti-Aβ Bispecific Antibody (Fab-scFv-scFv)  (CAT#: KN-1025-N38)

Recombinant Anti-INSR x Anti-Aβ Bispecific Antibody (Fab-scFv-scFv) is designed to be expressed as two polypeptide chains respectively. The Fd fragment and LC from one antibody are both extended with the scFv fragment from the other antibody. This BsAb can deliver the anti-Aβ antibody cross the blood-brain barrier (BBB). It is designed for the research of Alzheimer's disease therapy.
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Specifications

Targets
INSR & Aβ
Type
Fab-scFv-scFv
Species Reactivity
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Alzheimer's disease
Host Animal 1
Mouse
Host Animal 2
Mouse

Targets

Target 1
INSR
Gene ID
UniProt ID
Alternative Names
CD220; Insulin receptor; INSR; HHF5; EC:2.7.10.1; IR; Insulin receptor subunit alpha; Insulin receptor subunit beta
Target 2
Gene ID
UniProt ID
Alternative Names
APP; amyloid beta precursor protein; AAA; AD1; PN2; ABPP; APPI; CVAP; ABETA; PN-II; preA4; CTFgamma
Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.
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