Home > Products > Kit & VCAM-1 > Recombinant Human Anti-Kit x Human Anti-VCAM-1 Bispecific Antibody (Fab-Fv)

Recombinant Human Anti-Kit x Human Anti-VCAM-1 Bispecific Antibody (Fab-Fv)  (FABFV-H344)

Recombinant Anti-Kit x Anti-VCAM-1 Bispecific Antibody (Fab-Fv) is designed to be expressed as two polypeptide chains. The heavy chain Fd fragment and light chain of an anti-Kit antibody are fused with the VL and VH domains of an anti-VCAM-1 antibody respectively. It can form natural in vivo heterodimerization. This BsAb can retarget hematopoietic stem cells toinjured myocardium. It is designed for the research of Cardiovascular disease therapy.

Specifications
Targets
Kit & VCAM-1
Type
Fab-Fv
Species Reactivity
Human
Target 1
Kit
Host Animal 1
Human
Target 2
VCAM-1
Host Animal 2
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Cardiovascular disease
Targets
Target 1
Kit
Gene ID
UniProt ID
Alternative Names
W; Bs; Fdc; Ssm; SCO1; SCO5; SOW3; CD117; c-KIT; Tr-kit; Gsfsco1; Gsfsco5; Gsfsow3; KIT proto-oncogene receptor tyrosine kinase; KIT
Target 2
VCAM-1
Gene ID
UniProt ID
Alternative Names
CD106, INCAM-100; Vascular cell adhesion molecule-1; VCAM-1; vascular cell adhesion protein 1
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