Recombinant Human Anti-Kit x Anti-VCAM-1 Bispecific Antibody (Fab-IgG) (FABIG-H343)

Recombinant Anti-Kit x Anti-VCAM-1 Bispecific Antibody (Fab-IgG) is designed to be expressed as three chains, assembling in vivo and resulting in the construct of Fab-IgG (Tandem Fab-Fc). Fab-IgG has standard Fab and Fc domains, with no mutations, which may permit it has similar affinity binding and PK profile comparable to the parental antibodies. This BsAb can retarget hematopoietic stem cells to injured myocardium. It is designed for the research of Cardiovascular disease therapy.

Datasheet INQUIRY

Specifications

Targets

Kit & VCAM-1

Type

Fab-IgG

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Cardiovascular disease

Targets

Target 1

Kit

Gene ID

3815

UniProt ID

A0A024RDA0

Alternative Names

W; Bs; Fdc; Ssm; SCO1; SCO5; SOW3; CD117; c-KIT; Tr-kit; Gsfsco1; Gsfsco5; Gsfsow3; KIT proto-oncogene receptor tyrosine kinase; KIT

Target 2

VCAM-1

Gene ID

7412

UniProt ID

P19320

Alternative Names

CD106, INCAM-100; Vascular cell adhesion molecule-1; VCAM-1; vascular cell adhesion protein 1

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Human Anti-Kit x Anti-VCAM-1 Bispecific Antibody (Fab-IgG) (CAT#: FABIG-H343)

Specifications

Targets

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