Home > Products > Kit & VCAM-1 > Recombinant Human Anti-Kit x Anti-VCAM-1 Bispecific Antibody (Fab-IgG)

Recombinant Human Anti-Kit x Anti-VCAM-1 Bispecific Antibody (Fab-IgG)  (FABIG-H343)

Recombinant Anti-Kit x Anti-VCAM-1 Bispecific Antibody (Fab-IgG) is designed to be expressed as three chains, assembling in vivo and resulting in the construct of Fab-IgG (Tandem Fab-Fc). Fab-IgG has standard Fab and Fc domains, with no mutations, which may permit it has similar affinity binding and PK profile comparable to the parental antibodies. This BsAb can retarget hematopoietic stem cells to injured myocardium. It is designed for the research of Cardiovascular disease therapy.

Specifications

Targets
Kit & VCAM-1
Type
Fab-IgG
Species Reactivity
Human
Target 1
Kit
Host Animal 1
Human
Target 2
VCAM-1
Host Animal 2
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Cardiovascular disease

Targets

Target 1
Kit
Gene ID
UniProt ID
Alternative Names
W; Bs; Fdc; Ssm; SCO1; SCO5; SOW3; CD117; c-KIT; Tr-kit; Gsfsco1; Gsfsco5; Gsfsow3; KIT proto-oncogene receptor tyrosine kinase; KIT
Target 2
VCAM-1
Gene ID
UniProt ID
Alternative Names
CD106, INCAM-100; Vascular cell adhesion molecule-1; VCAM-1; vascular cell adhesion protein 1

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Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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