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Recombinant Anti-Kit x Anti-VCAM-1 Bispecific Antibody (Fv-IgG)  (CAT#: BSDG-179)

Recombinant Anti-Kit x Anti-VCAM-1 Bispecific Antibody (Fv-IgG) is an appended IgG format, which has 2+2 antigen-binding valency. This dual variable domain IgG is generated by appending variable domains of an anti-Kit IgG with similar domains from an anti-VCAM-1 antibody via short peptide linkers, or vice versa. This BsAb can retarget hematopoietic stem cells toinjured myocardium. It is designed for the research of Cardiovascular disease therapy.
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Specifications

Targets
Kit & VCAM-1
Type
Appended IgGs
Species Reactivity
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Cardiovascular disease

Targets

Target 1
Kit
Gene ID
UniProt ID
Alternative Names
W; Bs; Fdc; Ssm; SCO1; SCO5; SOW3; CD117; c-KIT; Tr-kit; Gsfsco1; Gsfsco5; Gsfsow3; KIT proto-oncogene receptor tyrosine kinase; KIT
Target 2
VCAM-1
Gene ID
UniProt ID
Alternative Names
CD106, INCAM-100; Vascular cell adhesion molecule-1; VCAM-1; vascular cell adhesion protein 1
Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.
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