Home > Products > Kit & VCAM-1 > Recombinant Anti-Kit x Anti-VCAM-1 Bispecific Antibody (IgG-scFv)

Recombinant Anti-Kit x Anti-VCAM-1 Bispecific Antibody (IgG-scFv)  (IGFV-179)

Recombinant Anti-Kit x Anti-VCAM-1 Bispecific Antibody (IgG-scFv) is designed to be expressed as a LC and an extended HC with scFv moiety linked to the C terminus. It is a symmetric bispecific and tetravalent molecule, bivalent for each antigen specificity, 2+2 antigen-binding valency. This BsAb can retarget hematopoietic stem cells to injured myocardium. It is designed for the research of Cardiovascular disease therapy.

Datasheet
Specifications
Targets
Kit & VCAM-1
Type
IgG-scFv
Species Reactivity
Human
Target 1
Kit
Host Animal 1
Mouse
Target 2
VCAM-1
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Cardiovascular disease
Targets
Target 1
Kit
Gene ID
3815
UniProt ID
A0A024RDA0
Alternative Names
W; Bs; Fdc; Ssm; SCO1; SCO5; SOW3; CD117; c-KIT; Tr-kit; Gsfsco1; Gsfsco5; Gsfsow3; KIT proto-oncogene receptor tyrosine kinase; KIT
Target 2
VCAM-1
Gene ID
7412
UniProt ID
P19320
Alternative Names
CD106, INCAM-100; Vascular cell adhesion molecule-1; VCAM-1; vascular cell adhesion protein 1
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