Home > Products > Kit & VCAM-1 > Recombinant Anti-Kit x Anti-VCAM-1 Bispecific Antibody (Miniantibody)

Recombinant Anti-Kit x Anti-VCAM-1 Bispecific Antibody (Miniantibody)  (MNAB-179)

Recombinant Anti-Kit x Anti-VCAM-1 Bispecific Antibody (Miniantibody) is a fusion protein of two scFv fragments combined with distinct specificity. One scFv of an anti-Kit antibody variable domain is linked to another scFv of an anti-VCAM-1 antibody variable domain by a flexible hinge region. This BsAb format has the decreased size and better penetration than conventional IgGs in the clinical diagnostics and potentially therapy. This BsAb can retarget hematopoietic stem cells toinjured myocardium. It is designed for the research of Cardiovascular disease therapy.

Specifications
Targets
Kit & VCAM-1
Type
scFv-based Bispecific Fragments
Species Reactivity
Human
Target 1
Kit
Host Animal 1
Mouse
Target 2
VCAM-1
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Cardiovascular disease
Targets
Target 1
Kit
Gene ID
UniProt ID
Alternative Names
W; Bs; Fdc; Ssm; SCO1; SCO5; SOW3; CD117; c-KIT; Tr-kit; Gsfsco1; Gsfsco5; Gsfsow3; KIT proto-oncogene receptor tyrosine kinase; KIT
Target 2
VCAM-1
Gene ID
UniProt ID
Alternative Names
CD106, INCAM-100; Vascular cell adhesion molecule-1; VCAM-1; vascular cell adhesion protein 1

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