Recombinant Anti-Kit x Anti-VCAM-1 Bispecific Antibody (Miniantibody) (MNAB-179)

Recombinant Anti-Kit x Anti-VCAM-1 Bispecific Antibody (Miniantibody) is a fusion protein of two scFv fragments combined with distinct specificity. One scFv of an anti-Kit antibody variable domain is linked to another scFv of an anti-VCAM-1 antibody variable domain by a flexible hinge region. This BsAb format has the decreased size and better penetration than conventional IgGs in the clinical diagnostics and potentially therapy. This BsAb can retarget hematopoietic stem cells toinjured myocardium. It is designed for the research of Cardiovascular disease therapy.

Datasheet INQUIRY

Specifications

Targets

Kit & VCAM-1

Type

scFv-based Bispecific Fragments

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Cardiovascular disease

Targets

Target 1

Kit

Gene ID

3815

UniProt ID

A0A024RDA0

Alternative Names

W; Bs; Fdc; Ssm; SCO1; SCO5; SOW3; CD117; c-KIT; Tr-kit; Gsfsco1; Gsfsco5; Gsfsow3; KIT proto-oncogene receptor tyrosine kinase; KIT

Target 2

VCAM-1

Gene ID

7412

UniProt ID

P19320

Alternative Names

CD106, INCAM-100; Vascular cell adhesion molecule-1; VCAM-1; vascular cell adhesion protein 1

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-Kit x Anti-VCAM-1 Bispecific Antibody (Miniantibody) (CAT#: MNAB-179)

Specifications

Targets

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