Home > Products > Kit & VCAM-1 > Recombinant Human Anti-Kit x Human Anti-VCAM-1 Bispecific Antibody (scDiabody-CH3)

Recombinant Human Anti-Kit x Human Anti-VCAM-1 Bispecific Antibody (scDiabody-CH3)  (SCDBC-H344)

Recombinant Anti-Kit x Anti-VCAM-1 Bispecific Antibody (scDiabody-CH3) is a fusion protein of two scDiabodies connected together by a CH3 region. In single-chain Diabodies, an additional connecting linker is introduced between chains of the anti-Kit/anti-VCAM-1 diabody. The scDiabody with two specificities is fused to each of the CH3 chains to extend half-life. This BsAb can retarget hematopoietic stem cells toinjured myocardium. It is designed for the research of Cardiovascular disease therapy.

Specifications
Targets
Kit & VCAM-1
Type
Constant Domain-extended Bispecific Fragments
Species Reactivity
Human
Target 1
Kit
Host Animal 1
Human
Target 2
VCAM-1
Host Animal 2
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Cardiovascular disease
Targets
Target 1
Kit
Gene ID
UniProt ID
Alternative Names
W; Bs; Fdc; Ssm; SCO1; SCO5; SOW3; CD117; c-KIT; Tr-kit; Gsfsco1; Gsfsco5; Gsfsow3; KIT proto-oncogene receptor tyrosine kinase; KIT
Target 2
VCAM-1
Gene ID
UniProt ID
Alternative Names
CD106, INCAM-100; Vascular cell adhesion molecule-1; VCAM-1; vascular cell adhesion protein 1
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