Recombinant Anti-Kit x Anti-VCAM-1 Bispecific Antibody (scFv-CH1/CL) (BSCC-179)

Recombinant Anti-Kit x Anti-VCAM-1 Bispecific Antibody (scFv-CH1/CL) is designed to be expressed as two chains. One scFv from an anti-Kit antibody variable domain is fused to CH1 and the other scFv from an anti-VCAM-1 antibody variable domain fused to CL, or vice versa. And the CH1 and CL domains are linked covalently via a natural disulfide bond. This BsAb can retarget hematopoietic stem cells toinjured myocardium. It is designed for the research of Cardiovascular disease therapy.

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Specifications

Targets

Kit & VCAM-1

Type

scFv-based Bispecific Fragments

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Cardiovascular disease

Targets

Target 1

Kit

Gene ID

3815

UniProt ID

A0A024RDA0

Alternative Names

W; Bs; Fdc; Ssm; SCO1; SCO5; SOW3; CD117; c-KIT; Tr-kit; Gsfsco1; Gsfsco5; Gsfsow3; KIT proto-oncogene receptor tyrosine kinase; KIT

Target 2

VCAM-1

Gene ID

7412

UniProt ID

P19320

Alternative Names

CD106, INCAM-100; Vascular cell adhesion molecule-1; VCAM-1; vascular cell adhesion protein 1

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-Kit x Anti-VCAM-1 Bispecific Antibody (scFv-CH1/CL) (CAT#: BSCC-179)

Specifications

Targets

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