Recombinant Anti-Kit x Anti-VCAM-1 Bispecific Antibody (scFv-Fc)  (BSCFV-179)

Recombinant Anti-Kit x Anti-VCAM-1 Bispecific Antibody (scFv-Fc) is formed by fusing two different scFv fragments to the hinge and Fc regions, in which the Fc region are engineered by KIH. Two of scFv moiety has the antibody variable domain of either anti-Kit specificity or anti-VCAM-1 specificity, which produces bivalent IgG-like molecules with desired characteristics of intact antibodies. This BsAb can retarget hematopoietic stem cells toinjured myocardium. It is designed for the research of Cardiovascular disease therapy.

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