Home > Products > Kit & VCAM-1 > Recombinant Anti-Kit x Anti-VCAM-1 Bispecific Antibody (scFv-Fc)

Recombinant Anti-Kit x Anti-VCAM-1 Bispecific Antibody (scFv-Fc)  (BSCFV-179)

Recombinant Anti-Kit x Anti-VCAM-1 Bispecific Antibody (scFv-Fc) is formed by fusing two different scFv fragments to the hinge and Fc regions, in which the Fc region are engineered by KIH. Two of scFv moiety has the antibody variable domain of either anti-Kit specificity or anti-VCAM-1 specificity, which produces bivalent IgG-like molecules with desired characteristics of intact antibodies. This BsAb can retarget hematopoietic stem cells toinjured myocardium. It is designed for the research of Cardiovascular disease therapy.

Specifications
Targets
Kit & VCAM-1
Type
scFv-based Bispecific Fragments
Species Reactivity
Human
Target 1
Kit
Host Animal 1
Mouse
Target 2
VCAM-1
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Cardiovascular disease
Targets
Target 1
Kit
Gene ID
UniProt ID
Alternative Names
W; Bs; Fdc; Ssm; SCO1; SCO5; SOW3; CD117; c-KIT; Tr-kit; Gsfsco1; Gsfsco5; Gsfsow3; KIT proto-oncogene receptor tyrosine kinase; KIT
Target 2
VCAM-1
Gene ID
UniProt ID
Alternative Names
CD106, INCAM-100; Vascular cell adhesion molecule-1; VCAM-1; vascular cell adhesion protein 1

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