Recombinant Anti-Kit x Anti-VCAM-1 Bispecific Antibody (scFv-Fc-scFv) (BSTF-179)

Recombinant Anti-Kit x Anti-VCAM-1 Bispecific Antibody (scFv-Fc-scFv) is designed to be expressed as one chain, then assembled to a homodimer of bivalent scFv fragments and the Fc region of IgG. The anti-Kit scFv is fused to the N-terminus of Fc via a hinge region while another anti-VCAM-1 scFv is linked to the C-terminus of Fc. This scFv-Fc-scFv format has 2+2 antigen-binding valency by employing different scFv fragments. This BsAb can retarget hematopoietic stem cells toinjured myocardium. It is designed for the research of Cardiovascular disease therapy.

Datasheet INQUIRY

Specifications

Targets

Kit & VCAM-1

Type

scFv-based Bispecific Fragments

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Cardiovascular disease

Targets

Target 1

Kit

Gene ID

3815

UniProt ID

A0A024RDA0

Alternative Names

W; Bs; Fdc; Ssm; SCO1; SCO5; SOW3; CD117; c-KIT; Tr-kit; Gsfsco1; Gsfsco5; Gsfsow3; KIT proto-oncogene receptor tyrosine kinase; KIT

Target 2

VCAM-1

Gene ID

7412

UniProt ID

P19320

Alternative Names

CD106, INCAM-100; Vascular cell adhesion molecule-1; VCAM-1; vascular cell adhesion protein 1

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

Online Inquiry

Customer Reviews and Q&As

There are currently no customer reviews or questions for Recombinant Anti-Kit x Anti-VCAM-1 Bispecific Antibody (scFv-Fc-scFv) (BSTF-179). Click the button below to contact us or submit your feedback about this product.

Recombinant Anti-Kit x Anti-VCAM-1 Bispecific Antibody (scFv-Fc-scFv) (CAT#: BSTF-179)

Specifications

Targets

Customer Reviews and Q&As