Recombinant Anti-Kit x Anti-VCAM-1 Bispecific Antibody (Single-chain Diabody) (SCDB-H343)

Recombinant Anti-Kit x Anti-VCAM-1 Bispecific Antibody (Single-chain Diabody) is designed to be expressed as one polypeptide chain with four variable domains from two parental antibodies. The middle linker is long enough to form scFv dimers between the two diabody chains. This BsAb can retarget hematopoietic stem cells to injured myocardium. It is designed for the research of Cardiovascular disease therapy.

Datasheet

Specifications

Targets

Kit & VCAM-1

Type

Single-chain Diabody

Species Reactivity

Human

Target 1

Kit

Host Animal 1

Human

Target 2

VCAM-1

Host Animal 2

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Cardiovascular disease

Targets

Target 1

Kit

Gene ID

3815

UniProt ID

A0A024RDA0

Alternative Names

W; Bs; Fdc; Ssm; SCO1; SCO5; SOW3; CD117; c-KIT; Tr-kit; Gsfsco1; Gsfsco5; Gsfsow3; KIT proto-oncogene receptor tyrosine kinase; KIT

Target 2

VCAM-1

Gene ID

7412

UniProt ID

P19320

Alternative Names

CD106, INCAM-100; Vascular cell adhesion molecule-1; VCAM-1; vascular cell adhesion protein 1

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