Recombinant Anti-M2 x Anti-TCR (Vβ8) Bispecific Antibody (Diabody-CH3) (BSDBC-180)

Recombinant Anti-M2 x Anti-TCR (Vβ8) Bispecific Antibody (Diabody-CH3) is a fusion protein of two diabodies connected together by a CH3 region. In a diabody, the two scFvs with short linkers are from anti-M2 and anti-TCR (Vβ8) antibodies. The VH and VL domains form an inter-chain pairing. The diabody with different specificities is fused to each of the CH3 chains, which results in 2+2 antigen-binding valency and extends the half-life of this BsAb. This BsAb can retarget T cells to virus-infected cells. It is designed for the research of Inﬂuenza virus infection therapy.

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Specifications

Targets

M2 & TCR (Vβ8)

Type

Constant Domain-extended Bispecific Fragments

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Inﬂuenza virus infection

Targets

Target 1

Gene ID

956528

UniProt ID

P03428

Alternative Names

influenza virus M2 protein;M2

Target 2

TCR (Vβ8)

Gene ID

28588

Alternative Names

Trbv8; T cell receptor beta variable 8; TCR; T-cell receptor

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-M2 x Anti-TCR (Vβ8) Bispecific Antibody (Diabody-CH3) (CAT#: BSDBC-180)

Specifications

Targets

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