Recombinant Anti-M2 x Anti-TCR (Vβ8) Bispecific Antibody (scFv-Fc-scFv) (BSTF-180)

Recombinant Anti-M2 x Anti-TCR (Vβ8) Bispecific Antibody (scFv-Fc-scFv) is designed to be expressed as one chain, then assembled to a homodimer of bivalent scFv fragments and the Fc region of IgG. The anti-M2 scFv is fused to the N-terminus of Fc via a hinge region while another anti-TCR (Vβ8) scFv is linked to the C-terminus of Fc. This scFv-Fc-scFv format has 2+2 antigen-binding valency by employing different scFv fragments. This BsAb can retarget T cells to virus-infected cells. It is designed for the research of Inﬂuenza virus infection therapy.

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Specifications

Targets

M2 & TCR (Vβ8)

Type

scFv-Fc-scFv

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Inﬂuenza virus infection

Targets

Target 1

Gene ID

956528

UniProt ID

P03428

Alternative Names

influenza virus M2 protein;M2

Target 2

TCR (Vβ8)

Gene ID

28588

Alternative Names

Trbv8; T cell receptor beta variable 8; TCR; T-cell receptor

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-M2 x Anti-TCR (Vβ8) Bispecific Antibody (scFv-Fc-scFv) (CAT#: BSTF-180)

Specifications

Targets

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