Recombinant Anti-malaria antigen x Anti-TLR1 Bispecific Antibody (Diabody-CH3) (BSDBC-181)

Recombinant Anti-malaria antigen x Anti-TLR1 Bispecific Antibody (Diabody-CH3) is a fusion protein of two diabodies connected together by a CH3 region. In a diabody, the two scFvs with short linkers are from anti-malaria antigen and anti-TLR1 antibodies. The VH and VL domains form an inter-chain pairing. The diabody with different specificities is fused to each of the CH3 chains, which results in 2+2 antigen-binding valency and extends the half-life of this BsAb. This BsAb can retarget professional antigen-presenting cells (APCs) including DCs or NK cells to malaria antigen. It is designed for the research of Malaria therapy.

Datasheet INQUIRY

Specifications

Targets

malaria antigen & TLR1

Type

Constant Domain-extended Bispecific Fragments

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Malaria

Targets

Target 1

malaria antigen

Alternative Names

malaria antigen; parasitic protozoans

Target 2

TLR1

Gene ID

7096

UniProt ID

Q15399

Alternative Names

CD281; TIL; TIL. LPRS5; rsc786; TLR1; Toll-like receptor 1; TLR

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-malaria antigen x Anti-TLR1 Bispecific Antibody (Diabody-CH3) (CAT#: BSDBC-181)

Specifications

Targets

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