Recombinant Anti-malaria antigen x Anti-TLR1 Bispecific Antibody (Fab-scFv-Fc) (FABVC-181)

Recombinant Anti-malaria antigen x Anti-TLR1 Bispecific Antibody (Fab-scFv-Fc) requires expression of three polypeptide chains, encoding two heavy chains (Fc-containing chains) and one light chain, respectively. The Fab of anti-malaria antigen antibody variable domain is fused to the Fc-knob domain with a hinge region and the same as the scFv of anti-TLR1 to the Fc-hole domain, or vice versa. The Fab-Fc and scFv-Fc fragments can be paired via the interaction of the Fc regions. This BsAb can retarget professional antigen-presenting cells (APCs) including DCs or NK cells to malaria antigen. It is designed for the research of Malaria therapy.

Datasheet INQUIRY

Specifications

Targets

malaria antigen & TLR1

Type

Fab-Fc Fusion Proteins

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Malaria

Targets

Target 1

malaria antigen

Alternative Names

malaria antigen; parasitic protozoans

Target 2

TLR1

Gene ID

7096

UniProt ID

Q15399

Alternative Names

CD281; TIL; TIL. LPRS5; rsc786; TLR1; Toll-like receptor 1; TLR

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-malaria antigen x Anti-TLR1 Bispecific Antibody (Fab-scFv-Fc) (CAT#: FABVC-181)

Specifications

Targets

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