Recombinant Anti-malaria antigen x Anti-TLR1 Bispecific Antibody (Miniantibody) is a fusion protein of two scFv fragments combined with distinct specificity. One scFv of an anti-malaria antigen antibody variable domain is linked to another scFv of an anti-TLR1 antibody variable domain by a flexible hinge region. This BsAb format has the decreased size and better penetration than conventional IgGs in the clinical diagnostics and potentially therapy. This BsAb can retarget professional antigen-presenting cells (APCs) including DCs or NK cells to malaria antigen. It is designed for the research of Malaria therapy.
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