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Recombinant Anti-mCD3 x Anti-mECD8 Bispecific Antibody (Tandem Fab)  (CAT#: KN-0125-N4)

Recombinant Anti-mCD3 x Anti-mCD8 Bispecific Antibody (Tandem Fab) is designed to be expressed as three chains derived from the variable domains of anti-mCD3 and anti-mCD8 parental antibodies. It contains a His-tag for affinity purification. And the two Fd regions are connected by a flexible linker. This BsAb can retarget T cells to HIV infected cells. It is designed for the research of HIV-1 infection, AIDS therapy.
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Specifications

Targets
CD3 & CD8
Type
Tandem Fab
Species Reactivity
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
HIV-1 infection, AIDS
Host Animal 1
Hamster
Host Animal 2
Rat

Targets

Target 1
CD3
Gene ID
UniProt ID
Alternative Names
CD3; CD3E; CD3e molecule; Cluster of differentiation 3; CD3e molecule, epsilon (CD3-TCR complex); T3E; TCRE; IMD18; T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell antigen receptor complex, epsilon subunit of T3
Target 2
CD8
Gene ID
UniProt ID
Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.
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