Recombinant Anti-NGF x Anti-TNF Bispecific Antibody (Tandem Fab) (BSFAB-182)

Recombinant Anti-NGF x Anti-TNF Bispecific Antibody (Tandem Fab) is designed to be expressed as three chains derived from the variable domains of anti-NGF and anti-TNF parental antibodies. It contains a His-tag for affinity purification. And the two Fd regions are connected by a flexible linker. This BsAb can bind and inactivate two ligands simultaneously. It is designed for the research of Osteoarthritis therapy.

Datasheet INQUIRY

Specifications

Targets

NGF & TNF

Type

Tandem Fab

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Osteoarthritis

Targets

Target 1

NGF

Gene ID

4803

UniProt ID

P01138

Alternative Names

nerve growth factor; NGF; NGFB; HSAN5; Beta-NGF; beta-nerve growth factor

Target 2

TNF

Gene ID

7124

UniProt ID

P01375

Alternative Names

TNF; tumor necrosis factor; DIF; TNFA; TNFSF2; TNF-alpha; TNFα; cachectin; APC1 protein; TNF, monocyte-derived; TNF-α; TNF, macrophage-derived; tumor necrosis factor-alpha; tumor necrosis factor ligand superfamily member 2

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

Online Inquiry

Customer Reviews and Q&As

There are currently no customer reviews or questions for Recombinant Anti-NGF x Anti-TNF Bispecific Antibody (Tandem Fab) (BSFAB-182). Click the button below to contact us or submit your feedback about this product.

Recombinant Anti-NGF x Anti-TNF Bispecific Antibody (Tandem Fab) (CAT#: BSFAB-182)

Specifications

Targets

Customer Reviews and Q&As