Name: Recombinant Human Anti-NkG2C x Mouse Anti-CD123 Bispecific Antibody (scFv-Fc)
SKU: KN-0725-N58
Rating: 5 (1 reviews)

Recombinant Human Anti-NkG2C x Mouse Anti-CD123 Bispecific Antibody (scFv-Fc) is formed by fusing two different scFv fragments to the hinge and Fc regions, in which the Fc region are engineered by KIH. Two of scFv moiety has the antibody variable domain of either anti-NkG2C specificity or anti-CD123 specificity, which produces bivalent IgG-like molecules with desired characteristics of intact antibodies. This BsAb can retarget NK cells to tumor cells. It is designed for the research of B cell lymphoma; Follicular lymphoma; Leukemia therapy.

Datasheet INQUIRY

Specifications

Targets

NkG2C & CD123

Type

scFv-Fc

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Acute myelogenous leukemia (AML); Chronic myelogenous leukemia (CML); Plasmacytoid leukemia

Host Animal 1

Human

Host Animal 2

Mouse

Targets

Target 1

NkG2C

Gene ID

3822

UniProt ID

P26717

Alternative Names

CD159c; Cluster of Differentiation 159c; Killer Cell Lectin-Like Receptor Subfamily C, Member 2; NKG2-C; NK cell receptor C-type lectin domain family 2 member C; NKG2C; NKG2-C type II integral membrane protein; CD159 antigen-like family member C; NK cell receptor C; NKG2-C-activating NK receptor; KLRC2; killer cell lectin like receptor C2

Target 2

CD123

Gene ID

3563

UniProt ID

P26951

Alternative Names

IL3RA; Cluster of differentiation 123; interleukin 3 receptor subunit alpha; IL3R; CD123; IL3RX; IL3RY; IL3RAY; hIL-3Ra

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Human Anti-NkG2C x Mouse Anti-CD123 Bispecific Antibody (scFv-Fc) (CAT#: KN-0725-N58)

Specifications

Targets

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