Name: Recombinant Human Anti-NkG2C x Mouse Anti-GPC3 Bispecific Antibody (IgG(H)-scFv)
SKU: KN-0725-N22
Rating: 5 (1 reviews)

Recombinant Human Anti-NkG2C x Mouse Anti-GPC3 Bispecific Antibody (IgG(H)-scFv) is designed to be expressed as a LC and an extended HC with scFv moiety linked to the C terminus. The anti-NkG2C scFvs are fused to the C terminus of the anti-GPC3 IgG-Fc chain. It is a symmetric bispecific and tetravalent molecule, bivalent for each antigen specificity, 2+2 antigen-binding valency. This BsAb can retarget NK cells to tumor cells. It is designed for the research of Hepatocellular cancer (HCC); Melanoma therapy.

Datasheet INQUIRY

Specifications

Targets

NkG2C & GPC3

Type

IgG-scFv

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Hepatocellular cancer (HCC); Melanoma

Host Animal 1

Human

Host Animal 2

Mouse

Targets

Target 1

NkG2C

Gene ID

3822

UniProt ID

P26717

Alternative Names

CD159c; Cluster of Differentiation 159c; Killer Cell Lectin-Like Receptor Subfamily C, Member 2; NKG2-C; NK cell receptor C-type lectin domain family 2 member C; NKG2C; NKG2-C type II integral membrane protein; CD159 antigen-like family member C; NK cell receptor C; NKG2-C-activating NK receptor; KLRC2; killer cell lectin like receptor C2

Target 2

GPC3

Gene ID

2719

UniProt ID

P51654

Alternative Names

SGB; DGSX; MXR7; SDYS; SGBS; OCI-5; SGBS1; GTR2-2; GPC3; glypican 3

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Human Anti-NkG2C x Mouse Anti-GPC3 Bispecific Antibody (IgG(H)-scFv) (CAT#: KN-0725-N22)

Specifications

Targets

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