Name: Recombinant Human Anti-NkG2D x Mouse Anti-BCMA Bispecific Antibody (scFv-Fc)
SKU: KN-0725-N47
Rating: 5 (1 reviews)

Recombinant Human Anti-NkG2D x Mouse Anti-BCMA Bispecific Antibody (scFv-Fc) is formed by fusing two different scFv fragments to the hinge and Fc regions, in which the Fc region are engineered by KIH. Two of scFv moiety has the antibody variable domain of either anti-NkG2D specificity or anti-BCMA specificity, which produces bivalent IgG-like molecules with desired characteristics of intact antibodies. This BsAb can retarget NK cells to tumor cells. It is designed for the research of Multiple myeloma (MM) therapy.

Datasheet INQUIRY

Specifications

Targets

NkG2D & BCMA

Type

scFv-Fc

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Multiple myeloma (MM)

Host Animal 1

Human

Host Animal 2

Mouse

Targets

Target 1

NkG2D

Gene ID

22914

UniProt ID

P26718

Alternative Names

CD314; Cluster of Differentiation 314; KLRK1; Killer cell lectin-like receptor subfamily K member 1; NKG2-D; NK cell activating receptor NKG2D; Natural killer group 2D; KLR; NKG2D; D12S2489E; killer cell lectin like receptor K1; NKG2-D type II integral membrane protein; NK cell receptor D; NKG2-D-activating NK receptor

Target 2

BCMA

Gene ID

608

UniProt ID

Q02223

Alternative Names

TNFRSF17; tumor necrosis factor receptor superfamily, member 17; BCM; BCMA; CD269; TNFRSF13A; tumor necrosis factor receptor superfamily member 17; B-cell maturation factor; B cell maturation antigen; B-cell maturation protein

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Human Anti-NkG2D x Mouse Anti-BCMA Bispecific Antibody (scFv-Fc) (CAT#: KN-0725-N47)

Specifications

Targets

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