Name: Recombinant Human Anti-NkG2D x Mouse Anti-CD123 Bispecific Antibody (Tandem Fab)
SKU: KN-0725-N82
Rating: 5 (1 reviews)

Recombinant Human Anti-NkG2D x Mouse Anti-CD123 Bispecific Antibody (Tandem Fab) is designed to be expressed as three chains derived from the variable domains of anti-NkG2D and anti-CD123 parental antibodies. It contains a His-tag for affinity purification. And the two Fd regions are connected by a flexible linker. This BsAb can retarget NK cells to tumor cells. It is designed for the research of B cell lymphoma; Follicular lymphoma; Leukemia therapy.

Datasheet INQUIRY

Specifications

Targets

NkG2D & CD123

Type

Tandem Fab

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Acute myelogenous leukemia (AML); Chronic myelogenous leukemia (CML); Plasmacytoid leukemia

Host Animal 1

Human

Host Animal 2

Mouse

Targets

Target 1

NkG2D

Gene ID

22914

UniProt ID

P26718

Alternative Names

CD314; Cluster of Differentiation 314; KLRK1; Killer cell lectin-like receptor subfamily K member 1; NKG2-D; NK cell activating receptor NKG2D; Natural killer group 2D; KLR; NKG2D; D12S2489E; killer cell lectin like receptor K1; NKG2-D type II integral membrane protein; NK cell receptor D; NKG2-D-activating NK receptor

Target 2

CD123

Gene ID

3563

UniProt ID

P26951

Alternative Names

IL3RA; Cluster of differentiation 123; interleukin 3 receptor subunit alpha; IL3R; CD123; IL3RX; IL3RY; IL3RAY; hIL-3Ra

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Human Anti-NkG2D x Mouse Anti-CD123 Bispecific Antibody (Tandem Fab) (CAT#: KN-0725-N82)

Specifications

Targets

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