Name: Recombinant Human Anti-NkG2D x Mouse Anti-CD30 Bispecific Antibody (scFv-Fc)
SKU: KN-0725-N45
Rating: 5 (1 reviews)

Recombinant Human Anti-NkG2D x Mouse Anti-CD30 Bispecific Antibody (scFv-Fc) is formed by fusing two different scFv fragments to the hinge and Fc regions, in which the Fc region are engineered by KIH. Two of scFv moiety has the antibody variable domain of either anti-NkG2D specificity or anti-CD30 specificity, which produces bivalent IgG-like molecules with desired characteristics of intact antibodies. This BsAb can retarget NK cells to tumor cells. It is designed for the research of Neuroblastoma; Osteosarcoma; Hodgkin lymphoma; T cell lymphoma; Anaplastic large cell lymphoma (ALCL) therapy.

Datasheet INQUIRY

Specifications

Targets

NkG2D & CD30

Type

scFv-Fc

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Neuroblastoma; Osteosarcoma; Hodgkin lymphoma; T cell lymphoma; Anaplastic large cell lymphoma (ALCL)

Host Animal 1

Human

Host Animal 2

Mouse

Targets

Target 1

NkG2D

Gene ID

22914

UniProt ID

P26718

Alternative Names

CD314; Cluster of Differentiation 314; KLRK1; Killer cell lectin-like receptor subfamily K member 1; NKG2-D; NK cell activating receptor NKG2D; Natural killer group 2D; KLR; NKG2D; D12S2489E; killer cell lectin like receptor K1; NKG2-D type II integral membrane protein; NK cell receptor D; NKG2-D-activating NK receptor

Target 2

CD30

Gene ID

943

UniProt ID

A5D8T4

Alternative Names

TNFRSF8; tumor necrosis factor receptor superfamily, member 8; CD30; Ki-1; D1S166E; tumor necrosis factor receptor superfamily member 8; Ki-1 antigen; CD30L receptor; cytokine receptor CD30; lymphocyte activation antigen CD30

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

Online Inquiry

Customer Reviews and Q&As

There are currently no customer reviews or questions for Recombinant Human Anti-NkG2D x Mouse Anti-CD30 Bispecific Antibody (scFv-Fc) (KN-0725-N45). Click the button below to contact us or submit your feedback about this product.

Recombinant Human Anti-NkG2D x Mouse Anti-CD30 Bispecific Antibody (scFv-Fc) (CAT#: KN-0725-N45)

Specifications

Targets

Customer Reviews and Q&As