Name: Recombinant Human Anti-NkG2D x Mouse Anti-GPC3 Bispecific Antibody (Tandem Fab)
SKU: KN-0725-N84
Rating: 5 (1 reviews)

Recombinant Human Anti-NkG2D x Mouse Anti-GPC3 Bispecific Antibody (Tandem Fab) is designed to be expressed as three chains derived from the variable domains of anti-NkG2D and anti-GPC3 parental antibodies. It contains a His-tag for affinity purification. And the two Fd regions are connected by a flexible linker. This BsAb can retarget NK cells to tumor cells. It is designed for the research of Hepatocellular cancer (HCC); Melanoma therapy.

Datasheet INQUIRY

Specifications

Targets

NkG2D & GPC3

Type

Tandem Fab

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Hepatocellular cancer (HCC); Melanoma

Host Animal 1

Human

Host Animal 2

Mouse

Targets

Target 1

NkG2D

Gene ID

22914

UniProt ID

P26718

Alternative Names

CD314; Cluster of Differentiation 314; KLRK1; Killer cell lectin-like receptor subfamily K member 1; NKG2-D; NK cell activating receptor NKG2D; Natural killer group 2D; KLR; NKG2D; D12S2489E; killer cell lectin like receptor K1; NKG2-D type II integral membrane protein; NK cell receptor D; NKG2-D-activating NK receptor

Target 2

GPC3

Gene ID

2719

UniProt ID

P51654

Alternative Names

SGB; DGSX; MXR7; SDYS; SGBS; OCI-5; SGBS1; GTR2-2; GPC3; glypican 3

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Human Anti-NkG2D x Mouse Anti-GPC3 Bispecific Antibody (Tandem Fab) (CAT#: KN-0725-N84)

Specifications

Targets

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