Name: Recombinant Human Anti-Nkp30 x Mouse Anti-GPC3 Bispecific Antibody (IgG(H)-scFv)
SKU: KN-0725-N28
Rating: 5 (1 reviews)

Recombinant Human Anti-Nkp30 x Mouse Anti-GPC3 Bispecific Antibody (IgG(H)-scFv) is designed to be expressed as a LC and an extended HC with scFv moiety linked to the C terminus. The anti-Nkp30 scFvs are fused to the C terminus of the anti-GPC3 IgG-Fc chain. It is a symmetric bispecific and tetravalent molecule, bivalent for each antigen specificity, 2+2 antigen-binding valency. This BsAb can retarget NK cells to tumor cells. It is designed for the research of Hepatocellular cancer (HCC); Melanoma therapy.

Datasheet INQUIRY

Specifications

Targets

Nkp30 & GPC3

Type

IgG-scFv

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Hepatocellular cancer (HCC); Melanoma

Host Animal 1

Human

Host Animal 2

Mouse

Targets

Target 1

Nkp30

Gene ID

259197

UniProt ID

O14931

Alternative Names

NCR3; Natural Cytotoxicity Triggering Receptor 3; CD337; Cluster of Differentiation 337; CLEC2D; C-Type Lectin Domain Family 2 Member D; LY94; Lymphocyte Antigen 94; 1C7; MALS; LY117; NKp30; Activating natural killer receptor p30; Natural killer cell p30-related protein

Target 2

GPC3

Gene ID

2719

UniProt ID

P51654

Alternative Names

SGB; DGSX; MXR7; SDYS; SGBS; OCI-5; SGBS1; GTR2-2; GPC3; glypican 3

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Human Anti-Nkp30 x Mouse Anti-GPC3 Bispecific Antibody (IgG(H)-scFv) (CAT#: KN-0725-N28)

Specifications

Targets

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