Name: Recombinant Human Anti-Nkp44 x Mouse Anti-GPC3 Bispecific Antibody (Tandem Fab)
SKU: KN-0725-N108
Rating: 5 (1 reviews)

Recombinant Human Anti-Nkp44 x Mouse Anti-GPC3 Bispecific Antibody (Tandem Fab) is designed to be expressed as three chains derived from the variable domains of anti-Nkp44 and anti-GPC3 parental antibodies. It contains a His-tag for affinity purification. And the two Fd regions are connected by a flexible linker. This BsAb can retarget NK cells to tumor cells. It is designed for the research of Hepatocellular cancer (HCC); Melanoma therapy.

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Specifications

Targets

Nkp44 & GPC3

Type

Tandem Fab

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Hepatocellular cancer (HCC); Melanoma

Host Animal 1

Human

Host Animal 2

Mouse

Targets

Target 1

Nkp44

Gene ID

9436

UniProt ID

O95944

Alternative Names

CD336; Cluster of Differentiation 336; NCR2; Natural Cytotoxicity Triggering Receptor 2; NK-p44; Natural cytotoxicity triggering receptor 2; KLR2F; Killer cell lectin-like receptor subfamily 2 member F; LY95; CD336; NKP44; dJ149M18.1; Lymphocyte antigen 95 homolog; NK cell-activating receptor; Natural killer cell p44-related protein

Target 2

GPC3

Gene ID

2719

UniProt ID

P51654

Alternative Names

SGB; DGSX; MXR7; SDYS; SGBS; OCI-5; SGBS1; GTR2-2; GPC3; glypican 3

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Human Anti-Nkp44 x Mouse Anti-GPC3 Bispecific Antibody (Tandem Fab) (CAT#: KN-0725-N108)

Specifications

Targets

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