Name: Recombinant Human Anti-Nkp44 x Mouse Anti-HER2 Bispecific Antibody (Tandem Fab)
SKU: KN-0725-N110
Rating: 5 (1 reviews)

Recombinant Human Anti-Nkp44 x Mouse Anti-HER2 Bispecific Antibody (Tandem Fab) is designed to be expressed as three chains derived from the variable domains of anti-Nkp44 and anti-HER2 parental antibodies. It contains a His-tag for affinity purification. And the two Fd regions are connected by a flexible linker. This BsAb can retarget NK cells to tumor cells. It is designed for the research of Breast cancer; Gastric cancer; Prostate cacncer; Ovarian cancer; Solid tumors therapy.

Datasheet INQUIRY

Specifications

Targets

Nkp44 & HER2

Type

Tandem Fab

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Breast cancer; Gastric cancer; Prostate cacncer; Ovarian cancer; Solid tumors

Host Animal 1

Human

Host Animal 2

Mouse

Targets

Target 1

Nkp44

Gene ID

9436

UniProt ID

O95944

Alternative Names

CD336; Cluster of Differentiation 336; NCR2; Natural Cytotoxicity Triggering Receptor 2; NK-p44; Natural cytotoxicity triggering receptor 2; KLR2F; Killer cell lectin-like receptor subfamily 2 member F; LY95; CD336; NKP44; dJ149M18.1; Lymphocyte antigen 95 homolog; NK cell-activating receptor; Natural killer cell p44-related protein

Target 2

HER2

Gene ID

2064

UniProt ID

P04626

Alternative Names

ERBB2; erb-b2 receptor tyrosine kinase 2; NEU; NGL; HER2; TKR1; CD340; HER-2; MLN 19; HER-2/neu; receptor tyrosine-protein kinase erbB-2; herstatin; p185erbB2; proto-oncogene Neu; c-erb B2/neu protein; proto-oncogene c-ErbB-2; metastatic lymph node gene 19 protein; human epidermal growth factor receptor 2; neuro/glioblastoma derived oncogene homolog; tyrosine kinase-type cell surface receptor HER2; neuroblastoma/glioblastoma derived oncogene homolog; v-erb-b2 avian erythroblastic leukemia viral oncoprotein 2; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2; v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Human Anti-Nkp44 x Mouse Anti-HER2 Bispecific Antibody (Tandem Fab) (CAT#: KN-0725-N110)

Specifications

Targets

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