Name: Recombinant Human Anti-Nkp46 x Mouse Anti-CD123 Bispecific Antibody (scFv-Fc)
SKU: KN-0725-N40
Rating: 5 (1 reviews)

Recombinant Human Anti-Nkp46 x Mouse Anti-CD123 Bispecific Antibody (scFv-Fc) is formed by fusing two different scFv fragments to the hinge and Fc regions, in which the Fc region are engineered by KIH. Two of scFv moiety has the antibody variable domain of either anti-Nkp46 specificity or anti-CD123 specificity, which produces bivalent IgG-like molecules with desired characteristics of intact antibodies. This BsAb can retarget NK cells to tumor cells. It is designed for the research of B cell lymphoma; Follicular lymphoma; Leukemia therapy.

Datasheet INQUIRY

Specifications

Targets

Nkp46 & CD123

Type

scFv-Fc

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Acute myelogenous leukemia (AML); Chronic myelogenous leukemia (CML); Plasmacytoid leukemia

Host Animal 1

Human

Host Animal 2

Mouse

Targets

Target 1

Nkp46

Gene ID

9437

UniProt ID

O76036

Alternative Names

CD335; NCR1; Natural Cytotoxicity Triggering Receptor 1, gene symbol; NK-p46; Natural Killer Cell Activating Receptor p46; LY94; CD335; NKP46; NK-p46; Natural cytotoxicity triggering receptor 1; Lymphocyte antigen 94 homolog; NK cell-activating receptor; Natural killer cell p46-related protein; NCR1

Target 2

CD123

Gene ID

3563

UniProt ID

P26951

Alternative Names

IL3RA; Cluster of differentiation 123; interleukin 3 receptor subunit alpha; IL3R; CD123; IL3RX; IL3RY; IL3RAY; hIL-3Ra

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Human Anti-Nkp46 x Mouse Anti-CD123 Bispecific Antibody (scFv-Fc) (CAT#: KN-0725-N40)

Specifications

Targets

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