Name: Recombinant Human Anti-Nkp46 x Mouse Anti-CD123 Bispecific Antibody (Tandem Fab)
SKU: KN-0725-N76
Rating: 5 (1 reviews)

Recombinant Human Anti-Nkp46 x Mouse Anti-CD123 Bispecific Antibody (Tandem Fab) is designed to be expressed as three chains derived from the variable domains of anti-Nkp46 and anti-CD123 parental antibodies. It contains a His-tag for affinity purification. And the two Fd regions are connected by a flexible linker. This BsAb can retarget NK cells to tumor cells. It is designed for the research of B cell lymphoma; Follicular lymphoma; Leukemia therapy.

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Specifications

Targets

Nkp46 & CD123

Type

Tandem Fab

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Acute myelogenous leukemia (AML); Chronic myelogenous leukemia (CML); Plasmacytoid leukemia

Host Animal 1

Human

Host Animal 2

Mouse

Targets

Target 1

Nkp46

Gene ID

9437

UniProt ID

O76036

Alternative Names

CD335; NCR1; Natural Cytotoxicity Triggering Receptor 1, gene symbol; NK-p46; Natural Killer Cell Activating Receptor p46; LY94; CD335; NKP46; NK-p46; Natural cytotoxicity triggering receptor 1; Lymphocyte antigen 94 homolog; NK cell-activating receptor; Natural killer cell p46-related protein; NCR1

Target 2

CD123

Gene ID

3563

UniProt ID

P26951

Alternative Names

IL3RA; Cluster of differentiation 123; interleukin 3 receptor subunit alpha; IL3R; CD123; IL3RX; IL3RY; IL3RAY; hIL-3Ra

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Human Anti-Nkp46 x Mouse Anti-CD123 Bispecific Antibody (Tandem Fab) (CAT#: KN-0725-N76)

Specifications

Targets

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