Recombinant Anti-OPN x Anti-VEGF Bispecific Antibody (Fab-Fv) (FABFV-183)

Recombinant Anti-OPN x Anti-VEGF Bispecific Antibody (Fab-Fv) is designed to be expressed as two polypeptide chains. The heavy chain Fd fragment and light chain of an anti-OPN antibody are fused with the VL and VH domains of an anti-VEGF antibody respectively. It can form natural in vivo heterodimerization. This BsAb can bind two factors simultaneously. It is designed for the research of Hepatocellular cancer; Metastatic cancer therapy.

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Specifications

Targets

OPN & VEGF

Type

Fab-Fv

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Hepatocellular cancer; Metastatic cancer

Targets

Target 1

OPN

Gene ID

6696

UniProt ID

A0A024RDE6

Alternative Names

OPN; BNSP; BSPI; ETA-1; Osteopontin; bone sialoprotein I; BSP-1; SPP1; secreted phosphoprotein 1

Target 2

VEGF

Gene ID

7422

UniProt ID

P15692

Alternative Names

VEGFA; vascular endothelial growth factor A; VPF; VEGF; MVCD1; vascular permeability factor

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-OPN x Anti-VEGF Bispecific Antibody (Fab-Fv) (CAT#: FABFV-183)

Specifications

Targets

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