Recombinant Human Anti-OPN x Anti-VEGF Bispecific Antibody (Fab-IgG) (FABIG-H345)

Recombinant Anti-OPN x Anti-VEGF Bispecific Antibody (Fab-IgG) is designed to be expressed as three chains, assembling in vivo and resulting in the construct of Fab-IgG (Tandem Fab-Fc). Fab-IgG has standard Fab and Fc domains, with no mutations, which may permit it has similar affinity binding and PK profile comparable to the parental antibodies. This BsAb can bind two factors simultaneously. It is designed for the research of Hepatocellular cancer; Metastatic cancer therapy.

Datasheet INQUIRY

Specifications

Targets

OPN & VEGF

Type

Fab-IgG

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Hepatocellular cancer; Metastatic cancer

Targets

Target 1

OPN

Gene ID

6696

UniProt ID

A0A024RDE6

Alternative Names

OPN; BNSP; BSPI; ETA-1; Osteopontin; bone sialoprotein I; BSP-1; SPP1; secreted phosphoprotein 1

Target 2

VEGF

Gene ID

7422

UniProt ID

P15692

Alternative Names

VEGFA; vascular endothelial growth factor A; VPF; VEGF; MVCD1; vascular permeability factor

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Human Anti-OPN x Anti-VEGF Bispecific Antibody (Fab-IgG) (CAT#: FABIG-H345)

Specifications

Targets

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