Home > Products > OPN & VEGF > Recombinant Human Anti-OPN x Human Anti-VEGF Bispecific Antibody (scFv-CH3)

Recombinant Human Anti-OPN x Human Anti-VEGF Bispecific Antibody (scFv-CH3)  (BSFC-H347)

Recombinant Anti-OPN x Anti-VEGF Bispecific Antibody (scFv-CH3) contains two chains. The anti-OPN scFv is fused to the Knob-CH3 domain via a hinge region and the same as the anti-VEGF scFv to the Hole-CH3 domain, or vice versa. The KIH CH3 domains can facilitate to form a heterodimer and this bivalent binding leads to improvement in avidity. This BsAb can bind two factors simultaneously. It is designed for the research of Hepatocellular cancer; Metastatic cancer therapy.

Specifications

Targets
OPN & VEGF
Type
scFv-based Bispecific Fragments
Species Reactivity
Human
Target 1
OPN
Host Animal 1
Mouse
Target 2
VEGF
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Hepatocellular cancer; Metastatic cancer

Targets

Target 1
OPN
Gene ID
UniProt ID
Alternative Names
OPN; BNSP; BSPI; ETA-1; Osteopontin; bone sialoprotein I; BSP-1; SPP1; secreted phosphoprotein 1
Target 2
VEGF
Gene ID
UniProt ID
Alternative Names
VEGFA; vascular endothelial growth factor A; VPF; VEGF; MVCD1; vascular permeability factor

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Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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