Name: Recombinant Human Anti-OPN x Human Anti-VEGF Bispecific Antibody (scFv-CH3)
SKU: BSFC-H347
Rating: 5 (1 reviews)

Recombinant Anti-OPN x Anti-VEGF Bispecific Antibody (scFv-CH3) contains two chains. The anti-OPN scFv is fused to the Knob-CH3 domain via a hinge region and the same as the anti-VEGF scFv to the Hole-CH3 domain, or vice versa. The KIH CH3 domains can facilitate to form a heterodimer and this bivalent binding leads to improvement in avidity. This BsAb can bind two factors simultaneously. It is designed for the research of Hepatocellular cancer; Metastatic cancer therapy.

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Specifications

Targets

OPN & VEGF

Type

scFv-CH3

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Hepatocellular cancer; Metastatic cancer

Host Animal 1

Mouse

Host Animal 2

Mouse

Targets

Target 1

OPN

Gene ID

6696

UniProt ID

A0A024RDE6

Alternative Names

OPN; BNSP; BSPI; ETA-1; Osteopontin; bone sialoprotein I; BSP-1; SPP1; secreted phosphoprotein 1

Target 2

VEGF

Gene ID

7422

UniProt ID

P15692

Alternative Names

VEGFA; vascular endothelial growth factor A; VPF; VEGF; MVCD1; vascular permeability factor

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Human Anti-OPN x Human Anti-VEGF Bispecific Antibody (scFv-CH3) (CAT#: BSFC-H347)

Specifications

Targets

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