Recombinant Anti-OPN x Anti-VEGF Bispecific Antibody (scFv-IgG) (BSSG-183)

Recombinant Anti-OPN x Anti-VEGF Bispecific Antibody (scFv-IgG) is formed by an IgG and two scFv fragments. The scFvs from an anti-OPN antibody variable domain are respectively connected to the N terminus of the anti-VEGF IgG heavy chains or light chains to form scFv-(H)IgG or scFv-(L)IgG. It is a type of appended IgGs and has 2+2 antigen-binding valency. This BsAb can bind two factors simultaneously. It is designed for the research of Hepatocellular cancer; Metastatic cancer therapy.

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Specifications

Targets

OPN & VEGF

Type

Appended IgGs

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Hepatocellular cancer; Metastatic cancer

Targets

Target 1

OPN

Gene ID

6696

UniProt ID

A0A024RDE6

Alternative Names

OPN; BNSP; BSPI; ETA-1; Osteopontin; bone sialoprotein I; BSP-1; SPP1; secreted phosphoprotein 1

Target 2

VEGF

Gene ID

7422

UniProt ID

P15692

Alternative Names

VEGFA; vascular endothelial growth factor A; VPF; VEGF; MVCD1; vascular permeability factor

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-OPN x Anti-VEGF Bispecific Antibody (scFv-IgG) (CAT#: BSSG-183)

Specifications

Targets

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