Name: Recombinant Anti-OPN x Anti-VEGF Bispecific Antibody (scFv4-Ig)
SKU: FVTIG-183
Rating: 5 (1 reviews)

Recombinant Anti-OPN x Anti-VEGF Bispecific Antibody (scFv4-Ig) is an appended IgG format, which includes four scFv moieties at the N-termini of the constant regions. It is a bivalent homodimer, in which one anti-OPN scFv is fused to the CH1 domain of a heavy chain and another anti-VEGF scFv to the CL domain of a light chain, or vice versa. The resulting leads to 2+2 antigen-binding valency. This BsAb can bind two factors simultaneously. It is designed for the research of Hepatocellular cancer; Metastatic cancer therapy.

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Specifications

Targets

OPN & VEGF

Type

scFv4-Ig

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Hepatocellular cancer; Metastatic cancer

Host Animal 1

Mouse

Host Animal 2

Mouse

Targets

Target 1

OPN

Gene ID

6696

UniProt ID

A0A024RDE6

Alternative Names

OPN; BNSP; BSPI; ETA-1; Osteopontin; bone sialoprotein I; BSP-1; SPP1; secreted phosphoprotein 1

Target 2

VEGF

Gene ID

7422

UniProt ID

P15692

Alternative Names

VEGFA; vascular endothelial growth factor A; VPF; VEGF; MVCD1; vascular permeability factor

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-OPN x Anti-VEGF Bispecific Antibody (scFv4-Ig) (CAT#: FVTIG-183)

Specifications

Targets

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