Home > Products > OPN & VEGF > Recombinant Human Anti-OPN x Human Anti-VEGF Bispecific Antibody (Tandem scFv-Fc)

Recombinant Human Anti-OPN x Human Anti-VEGF Bispecific Antibody (Tandem scFv-Fc)  (BSFVF-H347)

Recombinant Anti-OPN x Anti-VEGF Bispecific Antibody (Tandem scFv-Fc) is designed to be expressed as a homodimer, which has 2+2 antigen-binding valency. This format consists of one Fc region and two tandem scFv fragments, in which the anti-OPN/VEGF tandem scFv is fused to the Fc domain. The engineered fragment format is used to extend the half-life. This BsAb can bind two factors simultaneously. It is designed for the research of Hepatocellular cancer; Metastatic cancer therapy.

Specifications

Targets
OPN & VEGF
Type
Constant Domain-extended Bispecific Fragments
Species Reactivity
Human
Target 1
OPN
Host Animal 1
Human
Target 2
VEGF
Host Animal 2
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Hepatocellular cancer; Metastatic cancer

Targets

Target 1
OPN
Gene ID
UniProt ID
Alternative Names
OPN; BNSP; BSPI; ETA-1; Osteopontin; bone sialoprotein I; BSP-1; SPP1; secreted phosphoprotein 1
Target 2
VEGF
Gene ID
UniProt ID
Alternative Names
VEGFA; vascular endothelial growth factor A; VPF; VEGF; MVCD1; vascular permeability factor

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Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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