Recombinant Human Anti-PD1 x Human Anti-TIM-3 Bispecific Antibody (Miniantibody) (MNAB-H348)

Recombinant Anti-PD1 x Anti-TIM-3 Bispecific Antibody (Miniantibody) is a fusion protein of two scFv fragments combined with distinct specificity. One scFv of an anti-PD1 antibody variable domain is linked to another scFv of an anti-TIM-3 antibody variable domain by a flexible hinge region. This BsAb format has the decreased size and better penetration than conventional IgGs in the clinical diagnostics and potentially therapy. This BsAb can bind two receptors simultaneously and target unresponsive immune cells. It is designed for the research of Cancers therapy.

Datasheet INQUIRY

Specifications

Targets

PD1 & TIM-3

Type

scFv-based Bispecific Fragments

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Cancers

Targets

Target 1

PD1

Gene ID

5133

UniProt ID

Q15116

Alternative Names

PDCD1; programmed cell death 1; PD1; PD-1; CD279; SLEB2; hPD-1; hPD-l; hSLE1; programmed cell death protein 1; protein PD-1; systemic lupus erythematosus susceptibility 2

Target 2

TIM-3

Gene ID

84868

UniProt ID

Q8TDQ0

Alternative Names

TIM3; CD366; KIM-3; TIMD3; Tim-3; TIMD-3; HAVcr-2; T cell immunoglobulin and mucin domain 3; HAVCR2; hepatitis A virus cellular receptor 2

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Human Anti-PD1 x Human Anti-TIM-3 Bispecific Antibody (Miniantibody) (CAT#: MNAB-H348)

Specifications

Targets

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