Name: Recombinant Anti-PD1 x Anti-TIM-3 Bispecific Antibody (Tandem scFv-Fc)
SKU: BSFVF-185
Rating: 5 (1 reviews)

Recombinant Anti-PD1 x Anti-TIM-3 Bispecific Antibody (Tandem scFv-Fc) is designed to be expressed as a homodimer, which has 2+2 antigen-binding valency. This format consists of one Fc region and two tandem scFv fragments, in which the anti-PD1/TIM-3 tandem scFv is fused to the Fc domain. The engineered fragment format is used to extend the half-life. This BsAb can bind two receptors simultaneously and target unresponsive immune cells. It is designed for the research of Cancers therapy.

Datasheet INQUIRY

Specifications

Targets

PD1 & TIM-3

Type

Tandem scFv-Fc

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Cancers

Host Animal 1

Mouse

Host Animal 2

Mouse

Targets

Target 1

PD1

Gene ID

5133

UniProt ID

Q15116

Alternative Names

PDCD1; programmed cell death 1; PD1; PD-1; CD279; SLEB2; hPD-1; hPD-l; hSLE1; programmed cell death protein 1; protein PD-1; systemic lupus erythematosus susceptibility 2

Target 2

TIM-3

Gene ID

84868

UniProt ID

Q8TDQ0

Alternative Names

TIM3; CD366; KIM-3; TIMD3; Tim-3; TIMD-3; HAVcr-2; T cell immunoglobulin and mucin domain 3; HAVCR2; hepatitis A virus cellular receptor 2

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-PD1 x Anti-TIM-3 Bispecific Antibody (Tandem scFv-Fc) (CAT#: BSFVF-185)

Specifications

Targets

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