Recombinant Anti-PDGFR1 x Anti-VEGF Bispecific Antibody (Miniantibody) (MNAB-186)

Recombinant Anti-PDGFR1 x Anti-VEGF Bispecific Antibody (Miniantibody) is a fusion protein of two scFv fragments combined with distinct specificity. One scFv of an anti-PDGFR1 antibody variable domain is linked to another scFv of an anti-VEGF antibody variable domain by a flexible hinge region. This BsAb format has the decreased size and better penetration than conventional IgGs in the clinical diagnostics and potentially therapy. This BsAb can bind two antigens simultaneously. It is designed for the research of Neovascular ocular disorders; Cancers therapy.

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Specifications

Targets

PDGFR1 & VEGF

Type

scFv-based Bispecific Fragments

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Neovascular ocular disorders; Cancers

Targets

Target 1

PDGFR1

Gene ID

5159

UniProt ID

P09619

Alternative Names

IMF1; KOGS; IBGC4; JTK12; PDGFR; PENTT; CD140B; PDGFR1; PDGFR-1; PDGFRβ; platelet-derived growth factor receptor beta; PDGFRB

Target 2

VEGF

Gene ID

7422

UniProt ID

P15692

Alternative Names

VEGFA; vascular endothelial growth factor A; VPF; VEGF; MVCD1; vascular permeability factor

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-PDGFR1 x Anti-VEGF Bispecific Antibody (Miniantibody) (CAT#: MNAB-186)

Specifications

Targets

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