Recombinant Anti-PDGFR1 x Anti-VEGF Bispecific Antibody (scFv-Fc-scFv) is designed to be expressed as one chain, then assembled to a homodimer of bivalent scFv fragments and the Fc region of IgG. The anti-PDGFR1 scFv is fused to the N-terminus of Fc via a hinge region while another anti-VEGF scFv is linked to the C-terminus of Fc. This scFv-Fc-scFv format has 2+2 antigen-binding valency by employing different scFv fragments. This BsAb can bind two antigens simultaneously. It is designed for the research of Neovascular ocular disorders; Cancers therapy.
Welcome! For price inquiries, we will get back to you as soon as possible.
INQUIRY