Home > Products > PDGFR1 & VEGF > Recombinant Anti-PDGFR1 x Anti-VEGF Bispecific Antibody (Tandem scFv-Fc)

Recombinant Anti-PDGFR1 x Anti-VEGF Bispecific Antibody (Tandem scFv-Fc)  (BSFVF-186)

Recombinant Anti-PDGFR1 x Anti-VEGF Bispecific Antibody (Tandem scFv-Fc) is designed to be expressed as a homodimer, which has 2+2 antigen-binding valency. This format consists of one Fc region and two tandem scFv fragments, in which the anti-PDGFR1/VEGF tandem scFv is fused to the Fc domain. The engineered fragment format is used to extend the half-life. This BsAb can bind two antigens simultaneously. It is designed for the research of Neovascular ocular disorders; Cancers therapy.

Specifications
Targets
PDGFR1 & VEGF
Type
Constant Domain-extended Bispecific Fragments
Species Reactivity
Human
Target 1
PDGFR1
Host Animal 1
Mouse
Target 2
VEGF
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Neovascular ocular disorders; Cancers
Targets
Target 1
PDGFR1
Gene ID
UniProt ID
Alternative Names
IMF1; KOGS; IBGC4; JTK12; PDGFR; PENTT; CD140B; PDGFR1; PDGFR-1; PDGFRβ; platelet-derived growth factor receptor beta; PDGFRB
Target 2
VEGF
Gene ID
UniProt ID
Alternative Names
VEGFA; vascular endothelial growth factor A; VPF; VEGF; MVCD1; vascular permeability factor

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