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Recombinant Anti-PDGFR2 x Anti-VEGFR2 Bispecific Antibody (scFv-CH3) (CAT#: BSFC-187)
Recombinant Anti-PDGFR2 x Anti-VEGFR2 Bispecific Antibody (scFv-CH3) contains two chains. The anti-PDGFR2 scFv is fused to the Knob-CH3 domain via a hinge region and the same as the anti-VEGFR2 scFv to the Hole-CH3 domain, or vice versa. The KIH CH3 domains can facilitate to form a heterodimer and this bivalent binding leads to improvement in avidity. This BsAb can block two receptors simultaneously. It is designed for the research of Cancers therapy.
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