Recombinant Anti-PDGFR2 x Anti-VEGFR2 Bispecific Antibody (scFv-Fc) (BSCFV-187)

Recombinant Anti-PDGFR2 x Anti-VEGFR2 Bispecific Antibody (scFv-Fc) is formed by fusing two different scFv fragments to the hinge and Fc regions, in which the Fc region are engineered by KIH. Two of scFv moiety has the antibody variable domain of either anti-PDGFR2 specificity or anti-VEGFR2 specificity, which produces bivalent IgG-like molecules with desired characteristics of intact antibodies. This BsAb can block two receptors simultaneously. It is designed for the research of Cancers therapy.

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Specifications

Targets

PDGFR2 & VEGFR2

Type

scFv-based Bispecific Fragments

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Cancers

Targets

Target 1

PDGFR2

Gene ID

5156

UniProt ID

P16234

Alternative Names

PDGFRA; PDGFR2; platelet derived growth factor receptor, alpha polypeptide; CD140a; Pdgfr-2; AI115593; platelet-derived growth factor receptor alpha; PDGFR-alpha; PDGF-R-alpha; PDGF alpha chain; CD140 antigen-like family member A; platelet-derived growth factor alpha receptor; alpha-type platelet-derived growth factor receptor; Alpha platelet-derived growth factor receptor precursor (PDGF-R-alpha)

Target 2

VEGFR2

Gene ID

3791

UniProt ID

A0A024RD88

Alternative Names

FLK1; CD309; VEGFR; VEGFR2; Vascular endothelial growth factor receptor 2; Kinase insert domain receptor; Fetal liver kinase 1; Kinase insert domain receptor, a type III receptor; KDR

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-PDGFR2 x Anti-VEGFR2 Bispecific Antibody (scFv-Fc) (CAT#: BSCFV-187)

Specifications

Targets

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