Recombinant Human Anti-PDGFR2 x Human Anti-VEGFR2 Bispecific Antibody (Tandem scFv-Fc) (BSFVF-H350)

Recombinant Anti-PDGFR2 x Anti-VEGFR2 Bispecific Antibody (Tandem scFv-Fc) is designed to be expressed as a homodimer, which has 2+2 antigen-binding valency. This format consists of one Fc region and two tandem scFv fragments, in which the anti-PDGFR2/VEGFR2 tandem scFv is fused to the Fc domain. The engineered fragment format is used to extend the half-life. This BsAb can block two receptors simultaneously. It is designed for the research of Cancers therapy.

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Specifications

Targets

PDGFR2 & VEGFR2

Type

Constant Domain-extended Bispecific Fragments

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Cancers

Targets

Target 1

PDGFR2

Gene ID

5156

UniProt ID

P16234

Alternative Names

PDGFRA; PDGFR2; platelet derived growth factor receptor, alpha polypeptide; CD140a; Pdgfr-2; AI115593; platelet-derived growth factor receptor alpha; PDGFR-alpha; PDGF-R-alpha; PDGF alpha chain; CD140 antigen-like family member A; platelet-derived growth factor alpha receptor; alpha-type platelet-derived growth factor receptor; Alpha platelet-derived growth factor receptor precursor (PDGF-R-alpha)

Target 2

VEGFR2

Gene ID

3791

UniProt ID

A0A024RD88

Alternative Names

FLK1; CD309; VEGFR; VEGFR2; Vascular endothelial growth factor receptor 2; Kinase insert domain receptor; Fetal liver kinase 1; Kinase insert domain receptor, a type III receptor; KDR

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Human Anti-PDGFR2 x Human Anti-VEGFR2 Bispecific Antibody (Tandem scFv-Fc) (CAT#: BSFVF-H350)

Specifications

Targets

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