Recombinant Human Anti-SCLC1 x Human Anti-CD3 Bispecific Antibody (Single-chain Triplebody) (SCTB-H172)

Recombinant Anti-SCLC1 x Anti-CD3 Bispecific Antibody (Single-chain Triplebody) is designed to be expressed as a single chain with three scFv units, two distal binding sites for SCLC1 and a central site for CD3. It contains a His-tag at the C/N terminus for affinity purification. This BsAb can retarget T cells to tumor cells. It is designed for the research of Small cell lung cancer therapy.

Datasheet INQUIRY

Specifications

Targets

CD3 & SCLC1

Type

Single-chain Triplebody

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Small cell lung cancer

Targets

Target 1

CD3

Gene ID

916

UniProt ID

P07766

Alternative Names

CD3 (Cluster of differentiation 3), originally known as T3, is one of the first groups of human T lymphocyte surface antigens recognized by monoclonal antibodies. It has been reported that antibodies against CD3 could either stimulate T cells to divide or inhibit the progress of effector functions according to the conditions used. It plays an important role in T cell and the CD3 T-cell co-receptor helps to activate the cytotoxic T-Cell and T helper cells. The CD3 molecule is composed of a protein complex and consists of four distinct chains. The complex of mammals contains a CD3γ chain, a CD3δ chain, and two CD3ε chains. All these chains associate with T-cell receptor and the ζ-chain to generate an activation signal in T lymphocytes.

Target 2

SCLC1

Gene ID

7864

Alternative Names

SCCL; SCLC; SCLC1; small cell cancer of the lung

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

Online Inquiry

Customer Reviews and Q&As

There are currently no customer reviews or questions for Recombinant Human Anti-SCLC1 x Human Anti-CD3 Bispecific Antibody (Single-chain Triplebody) (SCTB-H172). Click the button below to contact us or submit your feedback about this product.

Recombinant Human Anti-SCLC1 x Human Anti-CD3 Bispecific Antibody (Single-chain Triplebody) (CAT#: SCTB-H172)

Specifications

Targets

Customer Reviews and Q&As