Home > Products > CD3 & TFRC > Recombinant Human Anti-TFRC x Human Anti-CD3 Bispecific Antibody (Single-chain Triplebody)

Recombinant Human Anti-TFRC x Human Anti-CD3 Bispecific Antibody (Single-chain Triplebody)  (SCTB-H173)

Recombinant Anti-TFRC x Anti-CD3 Bispecific Antibody (Single-chain Triplebody) is designed to be expressed as a single chain with three scFv units, two distal binding sites for TFRC and a central site for CD3. It contains a His-tag at the C/N terminus for affinity purification. This BsAb can retarget T cells to tumor cells. It is designed for the research of Erythroleukemia; Lymphoma therapy.

Specifications
Targets
CD3 & TFRC
Type
Single-chain Triplebody
Species Reactivity
Human
Target 1
CD3
Host Animal 1
Human
Target 2
TFRC
Host Animal 2
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Erythroleukemia; Lymphoma
Targets
Target 1
CD3
Gene ID
UniProt ID
Alternative Names
CD3 (Cluster of differentiation 3), originally known as T3, is one of the first groups of human T lymphocyte surface antigens recognized by monoclonal antibodies. It has been reported that antibodies against CD3 could either stimulate T cells to divide or inhibit the progress of effector functions according to the conditions used. It plays an important role in T cell and the CD3 T-cell co-receptor helps to activate the cytotoxic T-Cell and T helper cells. The CD3 molecule is composed of a protein complex and consists of four distinct chains. The complex of mammals contains a CD3γ chain, a CD3δ chain, and two CD3ε chains. All these chains associate with T-cell receptor and the ζ-chain to generate an activation signal in T lymphocytes.
Target 2
TFRC
Gene ID
UniProt ID
Alternative Names
TFRC; transferrin receptor; T9; TR; TFR; p90; CD71; TFR1; TRFR; transferrin receptor protein 1; transferrin receptor (p90, CD71)
Our services and products are only for lab research, not for any diagnostic or therapeutic use.

Welcome! For price inquiries, we will get back to you as soon as possible.

To order, please email

INQUIRY
Online Inquiry
Verification code
Click image to refresh the verification code.
USA
45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-381-2994
Fax: 1-631-207-8356
Email:

Germany
Heidenkampsweg 58, 20097 Hamburg, Germany
Email:

UK
167-169 Great Portland Street, 5th Floor, London, W1W 5PE
Tel: 44-207-097-1828
Email:
Related products of "CD3 & TFRC"
24x7 CUSTOMER SERVICE
Easy access to products and services you need from our library via
powerful searching tools
© 2021 Creative-Biolabs All Rights Reserved.
Distributors
To view the contact information for a specific location,
select your country or region: