Home > Products > CD3 & TFRC > Recombinant Anti-TFRC x Anti-CD3 Bispecific Antibody (Single-chain Triplebody)

Recombinant Anti-TFRC x Anti-CD3 Bispecific Antibody (Single-chain Triplebody)  (SCTB-H173)

Recombinant Anti-TFRC x Anti-CD3 Bispecific Antibody (Single-chain Triplebody) is designed to be expressed as a single chain with three scFv units, two distal binding sites for TFRC and a central site for CD3. It contains a His-tag at the C/N terminus for affinity purification. This BsAb can retarget T cells to tumor cells. It is designed for the research of Erythroleukemia; Lymphoma therapy.

Specifications
Targets
CD3 & TFRC
Type
Single-chain Triplebody
Species Reactivity
Human
Target 1
CD3
Host Animal 1
Human
Target 2
TFRC
Host Animal 2
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Erythroleukemia; Lymphoma
Targets
Target 1
CD3
Gene ID
UniProt ID
Alternative Names
CD3; CD3E; CD3e molecule; Cluster of differentiation 3; CD3e molecule, epsilon (CD3-TCR complex); T3E; TCRE; IMD18; T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell antigen receptor complex, epsilon subunit of T3
Target 2
TFRC
Gene ID
UniProt ID
Alternative Names
TFRC; transferrin receptor; T9; TR; TFR; p90; CD71; TFR1; TRFR; transferrin receptor protein 1; transferrin receptor (p90, CD71)

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