Recombinant Human Anti-TG x Human Anti-TPO Bispecific Antibody (F(ab')2-scFv2) (BABFV-H351)

Recombinant Anti-TG x Anti-TPO Bispecific Antibody (F(ab')2-scFv2) is designed to be expressed as two chains combined via a hinge region. The scFv of the anti-TG specificity is fused to the C terminus of the anti-TPO Fab fragment, or vice versa. This format comprises four binding sites (two same scFv regions and two same Fab fragments), two for each antigen. This BsAb can bind two antigens simultaneously and block the synthesis of thyroid hormones. It is designed for the research of Autoimmune thyroid disease therapy.

Datasheet INQUIRY

Specifications

Targets

TG & TPO

Type

Fab-Fc Fusion Proteins

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Autoimmune thyroid disease

Targets

Target 1

Gene ID

7038

UniProt ID

P01266

Alternative Names

AITD3, TG; thyroglobulin; TGN

Target 2

TPO

Gene ID

7173

UniProt ID

P07202

Alternative Names

MSA; TPX; TDH2A; TPPO; thrombopoietin; megakaryocyte growth and development factor; MGDF

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

Online Inquiry

Customer Reviews and Q&As

There are currently no customer reviews or questions for Recombinant Human Anti-TG x Human Anti-TPO Bispecific Antibody (F(ab')2-scFv2) (BABFV-H351). Click the button below to contact us or submit your feedback about this product.

Recombinant Human Anti-TG x Human Anti-TPO Bispecific Antibody (F(ab')2-scFv2) (CAT#: BABFV-H351)

Specifications

Targets

Customer Reviews and Q&As